Racial Differences in Strength of Associations Between Colorectal Cancer Screening, Area Deprivation, Demographics, and Clinical Characteristics

Background: In Louisiana, colorectal cancer (CRC) incidence and mortality exceed national rates. Census tract, sex, racial disparities across the state are well documented. This study examined whether there were subpopulation differences in associations between CRC screening, area deprivation index (ADI), patient characteristics. Methods: retrospective observational included patients aged 50 to 75 years who received care within Ochsner Health Louisiana July 1, 2012, December 31, 2020. Logistic regression models used generate adjusted odds ratios (95% CI). Results: A total of 75,344 met eligibility criteria for inclusion data analysis (60% female, 36% Black, 56% with spouse/partner, 42% Medicare/Medicaid,17% living high areas, 41% 2+ chronic conditions, never smoked, 51% obese). Living areas less (state decile 1-3 vs 8-10: 1.19 [1.14-1.24]), number comorbidities (3+ conditions: 1.15 [1.12-1.17]), prior outpatient visits (1.63 [1.58-1.67]) increased screening. Male sex (0.82 [0.79-0.84]), age group 55 59 (0.97 [0.95-0.99]), Medicaid insurance (0.89 [0.86-0.92]) decreased ADI was collinear race, marital status, body mass index, smoking status. subgroup analyses, between-group strength screening characteristics varied most prominently by race. Conclusion: There may be an unmeasured social context explaining persistent among factors associated combination census tract individual-level determinants guide population health management at-risk subpopulations.